Glucuronalactone (hereinafter referred to as DGL) is a natural metabolite of glucose and regulates the formation of glycogen.
This product is no longer in stock
Country | Ukraine |
Glucuronalactone (hereinafter referred to as DGL) is a natural metabolite of glucose and regulates the formation of glycogen. Its precursor, D-glucuronic acid (hereinafter referred to as DGA), remains in a state of equilibrium with glucuronolactone.
Therefore, at any given time, the compound can be converted back and forth to remain balanced in a 50/50 ratio endogenously (in the body).
The fact that two compounds, DGL and DGA, are physiologically interchangeable opens up a lot of empirical and scientifically based data about what DGL is and what its benefits as a sports supplement are. DGL can be found naturally in small amounts. Wine is the highest source (20 mg/l). Energy drinks average 2000-2400mg/L DGL, with a difference of 100-120 times. A number of studies have shown that even at high doses, the compound is relatively safe to use.
Studies have also shown that DGL is rapidly absorbed, metabolized and excreted as glucaric acid, xylitol (sugar alcohol), and L-xylulose (sugar) through the urine. So it can be considered that the compound is safe at additional doses (for example, 500-3000 mg.)
A very thorough, research-based European Commission paper examining the safety of energy drinks and their ingredients, including glucuronolactone, looked at toxicokinetics (the fate of compounds in the body) and effects.
"Consideration of the question of the chemical nature of the components and their metabolites, and the fact that different processes are involved in their absorption, distribution, metabolism and excretion, in the opinion of the expert, does not give rise to any reason to expect any toxicokinetic interactions, even at high dosages of any component ".
DGL is a hepatoprotector, which allows you to reduce the harmful effects and even improve the physical condition and function of the liver. In a Chinese study using Gan-Xian-Fan herbal blend, in which DGL is a component, they found marked improvement in patients with liver fibrosis suffering from hepatitis B.
A double controlled study, funded by the Chinese Ministry of Health and published in the Chinese Medical Journal, was conducted and provided evidence-based results. This study is not conclusive, given that DGL is not constrained by its actions, this enhances the potential and safety of the substance.
Testimonials from users using 1-3 grams of pure DGL, in powder form, generally report positive results in terms of energy and focus.
DGL is an interesting compound and is not only safe but also hepatoprotective. Of interest is the use of toxic metabolites (steroids) and the release of lipophilicity. DGL can increase the bioavailability of administered exogenous hormones, thereby causing an increase in the direct effect.
In addition, the compound may remove metabolites that may be potentially hepatotoxic and may be blocked to damage the liver. DGL may also provide ergogenic assistance by protecting glycogen stores and glycogenesis. Finally, it may serve to protect the athlete, potentially reducing the risk of injury and associated pain.
For a complete list of adaptogenic, stimulating and nootropic supplements, you can explore the catalog of the Proteininkiev online store.